Guizhou University was founded in 1902, and was named Guizhou University in October 1950 after the Guizhou University, Provincial Guizhou University, National Guizhou Institute of Agriculture and Industry, and National Guizhou University. In November 1951, Chairman Mao Zedong wrote the name of "Guizhou University" in his own handwriting. In August 1997, it merged with Guizhou Agricultural University and other universities. In August 2004, it merged with Guizhou University of Technology. In December 2004, it became a university jointly built by the Ministry of Education and the People's Government of Guizhou Province. In September 2005, it became a national "211 Project" university. In September 2017, it became a national world-class discipline construction university.